Endothelial Cells

Endothelial cells are specialized epithelial-like cells that line the interior surface of blood vessels and capillaries, forming a critical interface between the circulatory system and surrounding tissues. They regulate vascular permeability, blood flow, and angiogenesis, while playing a central role in inflammation, coagulation, and immune cell trafficking. In the brain, endothelial cells are key components of the blood–brain barrier, controlling molecular transport, maintaining vascular integrity, and supporting tissue homeostasis, making them essential in cardiovascular research, cancer biology, and studies of vascular and inflammatory disorders.